Taking hydroxychloroquine and methotrexate together is generally considered safe and is a common combination therapy for conditions like rheumatoid arthritis. Here are some key points:
Effectiveness: Combining these drugs can be more effective in reducing disease activity compared to methotrexate alone1.
Safety Profile: Hydroxychloroquine is well-tolerated and has a favorable safety profile. Methotrexate is also commonly used but requires regular monitoring due to potential liver toxicity.
Monitoring: Regular blood tests are necessary to monitor liver function and blood cell counts when taking these medications together.