Medications to Avoid with Hydroxychloroquine
Introduction
Hydroxychloroquine is used to treat autoimmune diseases and malaria. However, it can interact with various medications, leading to serious side effects. This essay explores the medications that should not be taken with hydroxychloroquine.
Medications Affecting Heart Rhythm
QT Prolongation
- Description: Hydroxychloroquine can prolong the QT interval, leading to arrhythmias.
- Examples:
- Cisapride
- Dronedarone
- Pimozide
- Thioridazine1
Antiarrhythmic Medications
- Description: These medications also affect heart rhythm and can increase the risk of arrhythmias.
- Examples:
Diabetes Medications
Blood Sugar Levels
- Description: Hydroxychloroquine can lower blood sugar levels, which can be dangerous when combined with diabetes medications.
- Examples:
Seizure Medications
Increased Seizure Risk
- Description: Hydroxychloroquine can lower the seizure threshold, increasing the risk of seizures.
- Examples:
- Phenytoin
- Carbamazepine2
Antacids
Absorption Issues
- Description: Antacids can interfere with the absorption of hydroxychloroquine, reducing its effectiveness.
- Examples:
- Magnesium hydroxide
- Aluminum hydroxide2
Cimetidine
Increased Hydroxychloroquine Levels
- Description: Cimetidine can increase hydroxychloroquine levels in the blood, leading to toxicity.
- Examples:
Cyclosporine
Increased Cyclosporine Levels
- Description: Hydroxychloroquine can increase cyclosporine levels, leading to toxicity.
- Examples:
- Neoral
- Sandimmune2
Methotrexate
Increased Risk of Side Effects
- Description: Combining these medications can increase the risk of side effects.
- Examples:
Other Medications
Various Interactions
- Description: Hydroxychloroquine can interact with a wide range of other medications.
- Examples:
- Gabapentin
- Atorvastatin
- Metoprolol3
Conclusion
Hydroxychloroquine can interact with many medications, leading to serious side effects. Always consult with your healthcare provider before starting or stopping any medication.